GTS GTS-2 IMMEDIAS VZGLYAD BIOSFERA LEGO LSO LSO-B LSO-S LSO-H POPULAR MECHANICS MPAC & SEED HDTV STARMAIL GCF-JAXA (NASDA) ROKVISS ETD NEUROCOG CARDIOCOG NEUROCOG-3 JAXA 3DPC JAXA 3DPC-2 SCN CARDIOCOG-4 NOA IMMUNO GOLF MYOCITE STROMA AMPHIBODY TUBUL MIA NKA BIOCULTURE ALTCRISS CULT Pille-ISS MATRIX Z1 Sample-LDM AT-SPACE BIOKIN 4 PKINASE EXPOSE-R

 
homepage
INTERNATIONAL SPACE STATION
EXPERIMENTS AND RESEARCHES

SCIENCE RESEARCH IN RUSSIAN SEGMENT
CONTRACT EXPERIMENTS AND ACTIVITIES
EXPERIMENT PKINASE
Principal Investigators: ESA, Medical Center, San Francisco (USA)
Research Manager: Millie Hughes-Fulford

russian
   

USED FLIGHT HARDWARE:

  • KUBIK incubator;
  • Glove Box

CONSUMABLES:

  • PKN experiment container (8)
 

OBJECTIVE:

Determine if the inhibition of protein kinase C (PKC) isoform signalling in human monocytes impairs monocyte differentiation.

TASK:

Characterize the microgravity effect on the activation of PKC isoforms and their spatial distribution.

EXPERIMENT RESULTS:

PKN return containers (8).

EXPECTED RESULTS:
  • Determine the microgravity effect on PKC regulated genes controlling monocyte differentiation, initiation of apoptosis and cell cycle arrest.
  • Prophylaxis of possible damage of a human immune system in spaceflight.
 

 

 

 

 

Official WEB-site of S.P.Korolev RSC Energia
E-mail:mail@rsce.ru