Русский

Contract activities on ISS Russian Segment

Experiment PKINASE


Objective:

Determine if the inhibition of protein kinase C (PKC) isoform signalling in human monocytes impairs monocyte differentiation.

Tasks:

Characterize the microgravity effect on the activation of PKC isoforms and their spatial distribution.

Science Hardware Used:

  • KUBIK incubator;
  • Glove Box.

Consumables:

  • PKN experiment container (8).

Experiment Results:

PKN return containers (8).

Expected Results:

  • Determine the microgravity effect on PKC regulated genes controlling monocyte differentiation, initiation of apoptosis and cell cycle arrest.
  • Prophylaxis of possible damage of a human immune system in spaceflight.

ISS Crew


OVCHININ Alexey OVCHININ
Alexey



HAGUE  Nick HAGUE
Nick



KOCH  Christina  KOCH
Christina



SKVORTSOV Alexandr SKVORTSOV
Alexandr



PARMITANO Luka PARMITANO
Luka



MORGAN   Andrew MORGAN
Andrew