Contract activities on ISS Russian Segment

Experiment PKINASE


Objective:

Determine if the inhibition of protein kinase C (PKC) isoform signalling in human monocytes impairs monocyte differentiation.

Tasks:

Characterize the microgravity effect on the activation of PKC isoforms and their spatial distribution.

Science Hardware Used:

  • KUBIK incubator;
  • Glove Box.

Consumables:

  • PKN experiment container (8).

Experiment Results:

PKN return containers (8).

Expected Results:

  • Determine the microgravity effect on PKC regulated genes controlling monocyte differentiation, initiation of apoptosis and cell cycle arrest.
  • Prophylaxis of possible damage of a human immune system in spaceflight.

ISS Crew


Hoshide  AkihikoHoshide
Akihiko



leg Novitskiy Novitskiy
leg



Petr Dubrov Dubrov
Petr



Mark Vande Hei Vande Hei
Mark



Robert Shane KIMBROUGH KIMBROUGH
Robert Shane



Megan McArthur McArthur
Megan



Thomas PESQUETPESQUET
Thomas