Biotechnological research on ISS Russian Segment
Compare specifics of heterologous expression of HbsAg gen of hepatitis B virus in yeasts S.cerevisiae under microgravity and gravity conditions and establish synthesis optimization techniques.
- Produce a clone collection of producer strain with heritable deviations in HbsAg gen expression level.
- Perform a genetic analysis and restriction mapping of plasmids and mutant clones.
Science Hardware Used :
“Bioecologia” kits (2), each consisting of 4 "Bioecologia" cases, which contain:
- Vial with an ampoule with lyophilized cultures (12);
- Tube with biosample vials (4);
- Temperature data logger.
"Bioecologia" cases with investigated organisms returned to the ground.
Obtaining maximum complete potential characteristics of heterologous expression of HbsAg gen of hepatitis B virus in yeasts S.cerevisiae. Thereafter new principles of increasing producers’ efficiency will be developed.