Science Research on ISS Russian Segment

Implementation of the program of scientific experiments of a South-African cosmonaut

ESCD Experiment


ESCD experiment is included in the scientific program of South African cosmonaut Mark Shuttleworth and is a constituent part of the Russian Program for Implementation of Scientific and Technological Research Planned for the Fourth Manned Expedition ISS-4.

Objective:

A study of embryonic and stem cell development in zero-gravity environment.

Tasks:

  • growing cultures of mammalian embryos (mice and sheep) in the incubator in zero gravity;
  • growing stem (undifferentiated) cells in incubator in zero gravity;
  • growing body (tissue) cells in incubator in zero gravity;
  • comparing cells that were experimentally grown in zero gravity with those grown in an incubator (in vitro) on the ground and in test animals (in vivo).

Scientific Equipment Used:

  • BioTherm incubator made by Cryologic (Australia) with a biological materials insert for actively thermostatting the biological materials at a temperature of 38.5.
  • Glovebox for accommodating inside it the incubator and an accessories box for the duration of the experiment in space flight environment.
  • Thermal insulation container CPCF-2 made by Astrium (Germany) to provide a thermally controlled storage environment for the biological materials insert during its transportation from orbit;
  • Accessories kit
    - syringes;
    - needles;
    - waste container;
    - adapter with power cord;
    - battery (a spare).

Support Equipment:

  • Camera NIKON F5.

Consumables:

  • 35-mm film.

Expected Results:

An evaluation of space flight factors impact on the viability and development of embryonic and stem cells outside an animal's body (in vitro) in order to obtain an in-depth knowledge of how these cells develop inside an animal's body (in vivo) and the level of effects produced by gravity.

ISS Crew


Hoshide  AkihikoHoshide
Akihiko



leg Novitskiy Novitskiy
leg



Petr Dubrov Dubrov
Petr



Mark Vande Hei Vande Hei
Mark



Robert Shane KIMBROUGH KIMBROUGH
Robert Shane



Megan McArthur McArthur
Megan



Thomas PESQUETPESQUET
Thomas